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" ... its action in the body during a relatively long period, and therefore of developing cumulative effects when repeated doses are administered. "
The Untoward effects of drugs: a pharmacological and clinical manual - Seite 160
von Louis Lewin - 1883 - 216 Seiten
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A Cyclopaedia of Drug Pathogenesy, Band 2

1888 - 776 Seiten
...faculty (which is probably due solely to an unusually slow elimination through the kidneys) of unfolding its action in the body during a relatively long period, and therefore of developing cumulative effects when repeated doses are administered. These may, under certain circumstances,...
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Medical consultation book

George P. Hachenberg - 1893 - 830 Seiten
...morphia to be owing to bad quality, having been partially transformed, by keeping, into apomorphia. DIGITALIS shares with only a few other drugs the property...latter may, under certain circumstances, give rise to symptoms of positive poisoning; these last are headache, dryness in the throat, nausea, choking, and...
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