Human Genetics. Proceedings of the 6th International Congress..., Sept. 13-18, 1981, Jerusalem: Medical aspects. II, Teil 2Batsheva Bonné-Tamir Liss, 1982 - 619 Seiten |
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Seite 78
... disease has been demonstrated , population data can also yield valuable information regarding the possible mode of inheritance of the HLA - linked “ disease ” gene . The expected frequencies in the diseased group of the antigen ...
... disease has been demonstrated , population data can also yield valuable information regarding the possible mode of inheritance of the HLA - linked “ disease ” gene . The expected frequencies in the diseased group of the antigen ...
Seite 84
... disease , in that it interacts with another unlinked locus to cause disease , can lead to erroneous and misleading results from linkage studies , and could explain the large recombination fractions reported above . Such a model would ...
... disease , in that it interacts with another unlinked locus to cause disease , can lead to erroneous and misleading results from linkage studies , and could explain the large recombination fractions reported above . Such a model would ...
Seite 85
... disease " allele are denoted f2 and fi respectively , with fz > f ;. Spielman et al ( 1980 ) have estimated that an intermediate model with f2 = 0.71 , fı = 0.065 , and PD 0.027 is compatible with observed population incidence data ...
... disease " allele are denoted f2 and fi respectively , with fz > f ;. Spielman et al ( 1980 ) have estimated that an intermediate model with f2 = 0.71 , fı = 0.065 , and PD 0.027 is compatible with observed population incidence data ...
Inhalt
Carrier Detection | 15 |
HLA and Infectious Diseases | 37 |
HLA and Diabetes | 55 |
Urheberrecht | |
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abnormalities activity addition affected allele analysis antigens appears association binding biochemical blood carrier cells changes chromosome clinical common complex cultured defect deficiency Department determined diabetes diabetes mellitus diagnosis disease disorders distribution dominant environmental enzyme estimated et al evidence expression factors fibroblasts findings frequency gene glucose haplotypes heterogeneity heterozygotes Hum Genet human hypertension IDDM immune important increased indicated individuals inheritance internalization involved Italy levels linkage linked locus lysosomal major marker measured Medical method mode of inheritance multiple mutant neural tube normal observed occur origin pairs parents patients phenotype population possible pregnancy prenatal present problems protein recently receptor recessive relative reported Research response risk screening showed shown significant specific structure studies suggested syndrome Table tissue trait translocation tumor twin ulcer University values York