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The mists of dawn had fled before
The fresh ’ning winds, when worn by sun and rain
A galleon from distant Spain

Sought haven on a solitary shore.
Long files of seafowl rode the breeze;
Bent pines and aged cypresses
Surmounted headlands rear'd above the strand
When ocean king smote king of land
To fix the everlasting bounds of each:
The deep-hewn fiord, the batter'd beach,

Half-routed phalanxes of rock,
Bore still the unforgiven scars of tempest shock.

Thus to a lonely wilderness,
Abode of chieftains deaf to mercy's plea,
There came across the chartless sea

A band of men inspir'd to serve and bless.
Straightway they set a sturdy hand
To sow the boundless unreap'd land;
To range the plains and winding cañons through
For clay and builder's stone; to hew
The massive blocks and fashion portal-sill,
Keystone and springing shaft, until

A tower'd minster crown'd the fell
And through the valleys rang its peace-proclaiming bell.
At length the toil-worn aged priest
Views well content the Easter feast,

The furrow'd land, the busy loom,

Fair homesteads girt with orchard bloom.But hold! the matin song has ceas'd;

Above the surf's eternal roar

The angelus is heard no more;
Over the arch's fallen rock

The buckthorn holds its ancient sway;
Gone is the priest that led the flock,

Gone is the flock he taught to pray.
Yet well the faithful servant's work was done,

Nor vain his zeal to banish hate and strife
From earth: else vainly too beneath the sun

The fragile lily struggles into life, Whose fleeting blossom sprung from lowly sod Lacks neither love of man nor benison of God.

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Two years ago, as Hitchcock lecturer to this University, I chose as my subject “Research in Medicine," and after sketching the role of observation and experiment in determining the progress of medicine, I devoted the final lecture to discussion of medical research in American universities and pointed out some of the facilities at that time existing, as well as the needs of and opportunities for research in our universities. In connection with these matters I naturally had in mind the University of California and I remember that I referred particularly to its opportunity, in view of the changed conditions resulting from the opening of the Panama Canal, in the study of tropical diseases. I did not say much-indeed I said nothing about its facilities for medical research, for, to be frank, I felt at that time that the men doing most creditable research were greatly handicapped by inadequate facilities. As to its needs, I covered these by discussing the needs of university medical schools in general and attempted to show how departments of research might be developed.

Little did I think at that time that in two short years I would be here to congratulate you upon the possession of a research foundation surpassing that of any university in this country, if not in the world, and which of all research foundations can be compared only with that of the Rockefeller Institute. I would be very happy if I could feel that my remarks of two years ago had anything to do with your present good fortune. I know they did not. Your present enviable position is solely the result of the two factors I mentioned at that time: (1) an influence outside the university, that is, the gradual awakening of the public to the importance of endowing research in medicine because of the value of the practical application of its results to the problems, prophylactic or therapeutic, hygienic or social, of the community, with all its differentiation into industrial, commercial, and domestic activities; and (2) an influence within the university, the desire of the university authorities to increase opportunities for investigation and thus serve the commonwealth which it represents, not only as a teacher of its youth, but also as an agent in a broader social service influencing all its people. It is most fortunate for the University of California that Mrs. Hooper who established this Foundation and the Regents who recognized the opportunities it offered, should both have been actuated by the same high ideal of aiding in the alleviation of suffering and the conquest of disease.

Now, how are these ideals to be realized. Your needs have been met and the facilities for research have been furnished. What is the opportunity and how is it to be utilized ? I find that my point of view has changed not at all in two years and I am forced to quote the closing words of the Hitchcock Lectures for 1912. “It is the duty of the University so to organize its laboratories and hospital that the advance of medicine by research may continue side by side with teaching, as a university function of benefit to student and faculty, as well as to the state and the general public welfare and thus as an aid to the advancement of civilization."

This, as I have learned in the last few days, is the policy and the ideal of the trustees of the Hooper Foundation. The plans of the University include the grouping of hospital, medical school and the Hooper Institute in one compact organization. Laboratory and clinic are to be side by side and the teacher, the investigator and the student of medicine are to be in intimate contact.

This is not the time or the place to talk of the details of this co-operation. Needless to say, the function and duty of the University as a teaching institute, should on its financial side be quite distinct from the research activities of the Hooper Foundation. The funds of the latter should not be diverted to the support of teaching or to eke out insufficient salaries, and, on the other hand, the existence of a research institute should not be used as an argument for the nonsupport of research in other departments of the medical school.

So also this new foundation should not be used for the maintenance of individuals or departments in the hospital not immediately concerned in investigation. To promote research is the sole and only function of the Hooper Foundation and to its trustees may be left the details of how this is to be done.

But of greater immediate interest, and more to the point, is the discussion of the opportunity offered the University in the way of fields of investigation. Problems in medical investigation may be grouped roughly as general, that is, those common to all communities, or local, as those determined by some peculiar condition of climate or geographical location, local industries, or density and character of population and so forth. The geographical situation of San Francisco determines one at least of the problems which should, through its new foundation, immediately engage the attention of the University of California. The port of San Francisco, draining as it does the Orient and soon to feel the influence of the Panama Canal, offers an opportunity for the study of tropical and unusual imported

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