LETTER OF TRANSMITTAL. BUREAU OF GOVERNMENT LABORATORIES, OFFICE OF THE SUPERINTENDENT, Manila, P. I., July 4, 1903. SIR: I have the honor to transmit herewith a report on "Trypanosoma and Trypanosomiasis, with special reference to surra, in the Philippine Islands," by W. E. Musgrave, M. D., Acting Director of the Biological Laboratory, and Moses T. Clegg, assistant bacteriologist, Biological Laboratory. Very respectfully, PAUL C. FREER, Superintendent of Government Laboratories. Hon. DEAN C. WORCESTER, Secretary of the Interior. LETTER OF SUBMITTAL. BUREAU OF GOVERNMENT LABORATORIES, BIOLOGICAL LABORATORY, Manila, P. I., July 4, 1903. SIR: In compliance with your request of July 1, 1902, I have the honor to submit herewith a report on "Trypanosoma and Trypanosomiasis, with special reference to Surra in the Philippine Islands." Very respectfully, W. E. MUSGRAVE, M. D., Acting Director Biological Laboratory. Dr. PAUL C. FREER, 4 Superintendent of Government Laboratories. V. Modes of transmission and infection-Continued. 6. Infection through the sound skin by biting or stinging insects. IX. Course, duration, and prognosis 180 X. Complications 181 XI. Diagnosis.. 181 XII. Differential diagnosis of surra, nagana, dourine, and mal de caderas 182 ILLUSTRATIONS. Page. FIG. 1. Showing insect-proof stable constructed for our experimental work 5. Illustrating the life cycle of Trypanosoma according to Schat 1 17 17 24 26 6-12. Trypanosoma equinum (multiplication and involution forms). 28 30 30 29-35. Trypanosoma evansii (Philippine Islands, multiplication forms). 31 36-41. Trypanosoma evansii (irregular dividing forms) - - 42. Trypanosoma evansii (peculiar phase of multiplication) 43-47. Trypanosoma agglomerations 34-35 36 37-39 48-49. Trypanosoma equinum (involution forms) 42 50-51. Trypanosoma equinum (involution forms). 43 52-59. Trypanosoma evansii (Philippine Islands, involution forms). 60. Trypanosoma sanguinis Gruby 44-45 52 i |